| Date | Home | Away | Result |
|---|---|---|---|
| 10/10/25 1:30 PM | FC Granada | UD Las Palmas | 0-0 |
| 10/11/25 9:15 AM | CD Mirandes | CD Leganes | 0-0 |
| 10/11/25 11:30 AM | Real Sociedad B | Andorra CF | 3-0 |
| 10/11/25 11:30 AM | UD Almeria | Real Saragossa | 4-2 |
| 10/12/25 7:00 AM | Albacete Balompie | AD Ceuta FC | 0-0 |
| 10/12/25 9:15 AM | Sporting Gijon | Racing Santander | 2-1 |
| 10/12/25 9:15 AM | SD Eibar | CD Castellon | 0-0 |
| 10/12/25 11:30 AM | Burgos CF | Real Valladolid | 0-1 |
| 10/12/25 11:30 AM | FC Cadiz | SD Huesca | 1-0 |
| 10/12/25 2:00 PM | FC Malaga | Deportivo La Coruna | 3-0 |
| 10/13/25 1:30 PM | Cordoba CF | CyD Leonesa | 1-0 |